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Case Study 02 · Neurology · First-in-Category Launch

From a single-market pilot to 11 markets — a pan-European neurology launch built on patient evidence.

11 European markets. 100,000+ data points generated across the patient community. Now embedded in European leadership decisions. A top-20 biopharma entering a rare neurology indication built the patient intelligence infrastructure that made their launches plannable — from a single-market pilot to European leadership.

Top-20 biopharma × mama health
Neurology · Rare Disease First-in-Category Launch 11 European countries Pilot → Pan-European
// Pilot → 11 markets
Pan-European scope 11 countries

A first-in-category neurology launch, anchored in patient evidence from market one.

By the numbers

The engagement, in evidence.

What this partnership produced — and the scale it reached.

// Scale
11
European countries unified under one patient journey at leadership level.
// Unified instrument
1
pan-European patient journey, with cross-market comparisons and strategic imperatives by country.
// Patient data generated
100k+
data points generated across the patient community — the deepest real-world dataset in the category.
The challenge
The context Two therapies recently approved in Europe for a rare neuromuscular condition. Deep immunology and rare disease expertise — but no prior commercial experience in the indication specifically.
The imperative A first-in-category launch demands a patient journey you don't have yet. There is no existing playbook to pressure-test — you have to build one from scratch.

A new indication. A pan-European patient intelligence infrastructure, built from scratch.

A top-20 biopharma brought deep expertise in immunology, autoimmune disease, and rare neurology. What they did not have was commercial history in the indication. No prior marketed product in this disease area. No established patient journey. No field narrative built on real-world patient experience in the space. Two therapies — both recently approved in Europe — were ready. The commercial infrastructure was not.

The launch window was open. The internal knowledge base was not.

In a first-in-category launch, you cannot pressure-test an existing patient journey — because there isn't one. You have to build the patient reality from scratch, at launch speed, while simultaneously standing up a commercial organisation around a disease the field has never engaged with before. Every assumption you make without evidence is a risk you carry into launch.

The engagement began as a pilot in one market, with six objectives defined jointly: map a comprehensive patient journey, profile and segment patients toward targeted therapies, understand the drivers and barriers to biologic access, drive patient awareness, integrate insights into patient support programmes, and establish the partner as a knowledge creator in the indication. Over 100,000 patient data points would ultimately be generated.

That pilot grew into one of the most comprehensive pan-European patient intelligence engagements mama health has run — from a single market to 11 countries, and from a project team to European leadership making decisions on the basis of it.

Every chart is answering a question I didn't think was answerable.
Insights & Analytics Lead Top 10 Pharma
How the engagement ran

Pilot. Expand. Elevate.

The engagement followed a three-phase structure — one market to establish the model, a second to deepen and operationalize, then elevation to a pan-European contract at leadership level. Each phase built directly on the one before it.

// Phase 01

Pilot in one market. Map the disease from the patient's perspective.

The pilot market was established as the starting point — both to prove the methodology and to begin building the patient reality the commercial team needed. The goal was comprehensive: understand disease burden, biologic access, and patient segments all at once.

01

Symptom and patient experience analysis

Deep-dived into fatigue, pain, and symptom evolution among patients in the indication to build a real-world picture of disease burden. This provided the commercial and medical teams with a grounded understanding of what patients actually experience — beyond what clinical trial populations reflect.

02

Biologic adoption and adherence deep dive

Analysed the drivers behind biologic adoption and the barriers to adherence, providing actionable commercial and medical intelligence. For a partner entering the biologic category in the indication for the first time, understanding why patients do and don't adopt — and stay on — targeted therapy was foundational to the launch strategy.

03

Patient persona profiling

Patient personas were developed based on jointly defined attributes — built with the partner's commercial and medical teams to ensure they mapped directly to the segmentation frameworks the field would use. Enabling more targeted engagement, more relevant support strategies, and a clearer picture of who the therapies would serve.

04

MSL field force enablement on the platform

The partner's Medical Science Liaison team was onboarded onto the mama health platform — extending reach and insight generation into the field. MSLs could now engage with real-world patient intelligence directly, rather than relying solely on internal summaries.

// Phase 02

Expand into a second market. Deepen and operationalize.

With the pilot model validated, the engagement expanded into a second European market. In parallel, findings were embedded across the partner's cross-functional team — moving insight from a research output to something the broader organisation could act on.

05

Cross-functional insight sharing

Insights from the pilot market were shared extensively across the partner's cross-functional team through multiple dedicated sessions — commercial, medical, and patient advocacy. The goal was not a single readout but sustained embedding of patient voice across functions.

06

Patient persona and biologic journey insights in the second market

Persona profiling and biologic adoption work from the pilot was replicated and refined within the context of the second market. Where the two markets diverged in patient behaviour or access dynamics, those differences became part of the cross-market picture building toward the pan-European view.

07

Patient empowerment quantification programme

A programme was initiated to quantify patient proactivity and capacity for empowerment within the second market — tracking how this evolves as the market matures. This longitudinal dimension added a time dimension to the patient journey that static research cannot capture.

// Phase 03

Elevate to European leadership. Unite 11 markets under one instrument.

The engagement was escalated from individual market pilots to a pan-European contract at the partner's European leadership level — spanning 11 countries. The output at this level was not more market-by-market data, but a unified patient journey and strategic imperatives that European leadership could act on.

08

Executive cross-country market view

European leadership received an executive-level view of the landscape across markets — drawing comparisons and surfacing where patient experience, biologic access, and market dynamics diverged. The executive view gave leadership the cross-country visibility needed to allocate resource and define priorities at scale.

09

Pan-European patient journey

A unified European-level patient journey was built — aggregating and comparing insight across all 11 markets. Not a collection of 11 separate journeys, but a single instrument that captured what was universal and what was market-specific, enabling leadership to plan at both levels simultaneously.

10

Strategic imperatives by country and joint publications

The European view enabled the definition of strategic imperatives for each country — identifying where patient support and market intervention was most needed. In parallel, a joint publications programme was initiated to establish the partner as a knowledge creator in the indication, converting internal intelligence into external thought leadership.

The results

11 markets. 100,000+ data points. Now driving leadership decisions.

What a top-20 biopharma built entering a rare neurology indication with no prior commercial playbook.

11 European markets, unified at leadership level
100k+ patient data points generated
3 phases — pilot to pan-European
01

11 countries. One instrument. European leadership, aligned.

What started as a pilot in a single European market is now a pan-European contract at the partner's European leadership level. Eleven countries. Cross-market comparisons. Strategic imperatives by country. The patient journey is not a research document — it is the instrument European leadership uses to decide where to act, how to allocate resource, and where the commercial organisation goes next. Patient evidence is now part of the decision room.

02

100,000+ data points. Zero remaining assumptions.

Across the full patient community engagement, over 100,000 data points were generated — covering disease burden, biologic adoption, treatment barriers, patient empowerment, and HCP dynamics. The partner entered this indication without a commercial playbook. They now have the deepest real-world patient intelligence dataset in the category, and an MSL field force running directly on the platform — carrying that intelligence into every HCP conversation.

03

In the decision room. In the field. In the literature.

Patient intelligence from this engagement now operates at three levels simultaneously. At European leadership — shaping commercial strategy and resource allocation across 11 markets. In the field — with MSLs onboarded onto the platform and engaging with real-world patient data directly. And in the scientific literature — through a joint publications programme converting internal intelligence into external thought leadership that establishes the partner as the knowledge creator in the indication.

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